Known targets — ChEMBL curated mechanism
CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8
The experimentally established mechanism targets of Phloroglucinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.89 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 6/20 | 0.50 |
| ▸ | CA9 | Q16790 | 6/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CA5A | P35218 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | BCR | P11274 | 2/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phloroglucinol SCHEMBL2889628 | 0.94 | BACE1 (1.00) | BACE1LCKCA12CA9CA2 | |
| Phloroglucinol SCHEMBL26311 | 0.94 | — | — | |
| Phloroglucinol SCHEMBL30542958 | 0.94 | — | — | |
| Phloroglucinol SCHEMBL10916023 | 0.89 | BACE1 (0.89) | BACE1LCKCA12CA9CA2 | |
| Phloroglucinol SCHEMBL5495237 | 0.89 | BACE1 (0.89) | BACE1LCKCA12CA9CA2 | |
| Phloroglucinol SCHEMBL23346245 | 0.89 | BACE1 (0.89) | BACE1LCKCA12CA9CA2 | |
| Phloroglucinol SCHEMBL31122758 | 0.89 | BACE1 (0.89) | BACE1LCKCA12CA9CA2 | |
| Phloroglucinol SCHEMBL1913949 | 0.89 | BACE1 (0.89) | BACE1LCKCA12CA9CA2 | |
| Phloroglucinol SCHEMBL310716 | 0.89 | BACE1 (0.89) | BACE1LCKCA12CA9CA2 | |
| Phloroglucinol SCHEMBL28934992 | 0.89 | BACE1 (0.89) | BACE1LCKCA12CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119985468-A | Method and system for detecting relative lignin content of plant sample | 海南大学 | 2025-05-13 | — | — | CN | claimed |
| CN-114107366-B | Efficient induction system for pear pulp callus lignin synthesis and application thereof | 南京农业大学 | 2023-09-22 | — | — | CN | claimed |
| CN-115728118-A | Plant tissue section counterstaining method | 西北农林科技大学 | 2023-03-03 | — | — | CN | claimed |
| CN-114107366-A | Efficient induction system for synthesizing lignin from pear pulp callus and application | 南京农业大学 | 2022-03-01 | — | — | CN | claimed |
| CN-122012607-A | Gene PbTCP for regulating and controlling pear fruit stone cells | 南京农业大学三亚研究院 | 2026-05-12 | — | — | CN | disclosed |
| CN-122012608-A | Gene PbMYB20 for regulating and controlling pear fruit stone cell formation | 南京农业大学三亚研究院 | 2026-05-12 | — | — | CN | disclosed |
| US-20260092333-A1 | METHOD FOR EVALUATING SEEDLING PLANT CHARACTER OF TRANSGENIC POPLAR AND USE OF OVEREXPRESSED PAGEXPA1 GENE IN PROMOTING XYLEM DEVELOPMENT OF POPLAR | RESEARCH INSTITUTE OF FORESTRY, CHINESE ACADEMY OF FORESTRY (CN) | 2026-04-02 | — | — | US | disclosed |
| CN-121575027-A | Method for cultivating low anti-nutritional factor and high-nutritional alfalfa and application | 中科国利农业(珠海)有限公司 | 2026-02-27 | — | — | CN | disclosed |
| CN-116199758-B | Pear transcription factor PbrMYB and application thereof in promoting synthesis of lignin and cellulose in stone cells | 南京农业大学 | 2025-12-02 | — | — | CN | disclosed |
| US-20250230461-A1 | MUTANT GENE OF ZMNST2 AND METHOD FOR IMPROVING EFFICIENCY OF BIOETHANOL PRODUCTION THROUGH FERMENTATION OF MAIZE STRAW | HENAN AGRICULTURAL UNIVERSITY (CN) | 2025-07-17 | — | — | US | disclosed |
| CN-119985468-A | Method and system for detecting relative lignin content of plant sample | 海南大学 | 2025-05-13 | — | — | CN | disclosed |
| CN-119985468-A | Method and system for detecting relative lignin content of plant sample | 海南大学 | 2025-05-13 | — | — | CN | disclosed |
| EP-1551984-A1 | A ROLE IN LIGNIFICATION AND GROWTH FOR PLANT PHENYLCOUMARAN BENZYLIC ETHER REDUCTASE | VIB vzw (BE) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004113528-A2 | ISOFORMS OF ELF-5A: SENESCENCE-INDUCED ELF5A; WOUNDING-INDUCED ELF-5A; GROWTH ELF-5A; AND DHS | SENESCO TECHNOLOGIES, INC. (US) | 2004-12-29 | — | — | WO | disclosed |
| CN-1517395-A | Hydroxypropyl-beta-cyclodextrin inclusion compound of anethole, preparation and preparation method thereof | 董英杰 | 2004-08-04 | — | — | CN | disclosed |
| WO-2004048579-A1 | A ROLE IN LIGNIFICATION AND GROWTH FOR PLANT PHENYLCOUMARAN BENZYLIC ETHER REDUCTASE | VIB VZW (BE) | 2004-06-10 | — | — | WO | disclosed |
| US-20040049802-A1 | Method for modifying lignin composition and increasing in vivo digestibility of forages | SAMUEL ROBERTS NOBLE FOUNDATION, INC. | 2004-03-11 | — | — | US | disclosed |
| US-6441272-B1 | REDUCING CONCENTRATION | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2002-08-27 | — | — | US | disclosed |
| WO-2001073090-A2 | METHOD FOR MODIFYING LIGNIN COMPOSITION AND INCREASING IN VIVO DIGESTIBILITY OF FORAGES | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2001-10-04 | — | — | WO | disclosed |
| WO-1994003065-A1 | BIOCONTROL OF FUNGAL INFECTION USING PSEUDOMONAS STRAINS | THE UNIVERSITY OF SYDNEY (AU) | 1994-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260092333-A1 | METHOD FOR EVALUATING SEEDLING PLANT CHARACTER OF TRANSGENIC POPLAR AND USE OF OVEREXPRESSED PAGEXPA1 GENE IN PROMOTING XYLEM DEVELOPMENT OF POPLAR | GUSB, GLB1, COLGALT1 | BACE1 3330/4885LCK 4485/4885CA12 4313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.