Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 7/20 | 0.33 |
| ▸ | CA1 | P00915 | 7/20 | 0.33 |
| ▸ | CA2 | P00918 | 7/20 | 0.33 |
| ▸ | CA9 | Q16790 | 7/20 | 0.33 |
| ▸ | CA7 | P43166 | 5/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29860029 | 1.00 | TSHR (0.48) | TSHRHCAR2CA12CA1CA2 | |
| SCHEMBL19256 | 0.97 | TSHR (0.50) | TSHRHCAR2CA12CA1CA2 | |
| SCHEMBL444245 | 0.97 | TSHR (0.50) | TSHRHCAR2CA12CA1CA2 | |
| SCHEMBL19257 | 0.97 | TSHR (0.50) | TSHRHCAR2CA12CA1CA2 | |
| Water SCHEMBL30250355 | 0.94 | TSHR (0.48) | TSHRHCAR2CA12CA1CA2 | |
| SCHEMBL28883041 | 0.94 | TSHR (0.48) | TSHRHCAR2CA12CA1CA2 | |
| SCHEMBL22690761 | 0.94 | TSHR (0.48) | TSHRHCAR2CA12CA1CA2 | |
| Bicarbonate SCHEMBL2348361 | 0.89 | TSHR (0.43) | TSHRHCAR2CA12CA1CA2 | |
| SCHEMBL25204408 | 0.87 | TSHR (0.42) | TSHRHCAR2CA12CA1CA2 | |
| SCHEMBL3787432 | 0.87 | TSHR (0.42) | TSHRHCAR2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113473987-B | Substituted 3- ((3-aminophenyl) amino) piperidine-2, 6-dione compounds, compositions thereof, and methods of treatment using the same | 细胞基因公司 | 2024-09-03 | — | — | CN | disclosed |