SCHEMBL444245

SCHEMBL444245

CC(C)OC(=O)/N=N\C(=O)OC(C)C

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
HCAR2 Q8TDS4 1/20 0.39
CA12 O43570 9/20 0.35
CA1 P00915 9/20 0.35
CA2 P00918 9/20 0.35
CA9 Q16790 9/20 0.35
CA7 P43166 7/20 0.34
CA14 Q9ULX7 7/20 0.34
LMNA P02545 3/20 0.34
AKR1B10 O60218 1/20 0.33
AKR1B1 P15121 1/20 0.33
ADRA1A P35348 1/20 0.33
PDE4D Q08499 1/20 0.33
KDM4E B2RXH2 1/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19256 1.00 TSHR (0.50) TSHRHCAR2CA12CA1CA2
SCHEMBL19257 1.00 TSHR (0.50) TSHRHCAR2CA12CA1CA2
Water SCHEMBL30250355 0.97 TSHR (0.48) TSHRHCAR2CA12CA1CA2
SCHEMBL22690761 0.97 TSHR (0.48) TSHRHCAR2CA12CA1CA2
SCHEMBL28883041 0.97 TSHR (0.48) TSHRHCAR2CA12CA1CA2
SCHEMBL29860029 0.97 TSHR (0.48) TSHRHCAR2CA12CA1CA2
SCHEMBL31071641 0.97 TSHR (0.48) TSHRHCAR2CA12CA1CA2
Bicarbonate SCHEMBL2348361 0.92 TSHR (0.43) TSHRHCAR2CA12CA1CA2
SCHEMBL23884961 0.89 TSHR (0.42) TSHRHCAR2CA12CA1CA2
SCHEMBL15843149 0.89 TSHR (0.42) TSHRHCAR2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720058-A2 BIFUNCTIONAL DEGRADERS AND USES THEREOF Casma Therapeutics, Inc. (US) 2026-04-08 EP disclosed
WO-2024249291-A2 BIFUNCTIONAL DEGRADERS AND USES THEREOF CASMA THERAPEUTICS, INC. (US) 2024-12-05 WO disclosed
CN-113365632-B Aminopyrimidine compounds 卡都瑞恩医药有限公司 2024-03-08 CN disclosed
WO-2023218149-A1 MIRROR THAT IS EASILY REMOVABLE FROM A SUPPORT TO WHICH IT HAS BEEN GLUED SAINT-GOBAIN GLASS FRANCE (FR) 2023-11-16 WO disclosed
WO-2023186893-A1 ADHESIVE COMPOSITION FOR A GLASS ITEM COMPRISING EXPANSION MEANS AND LAMINATED GLAZING UNIT FOR A MOTOR VEHICLE COMPRISING SUCH A COMPOSITION SAINT-GOBAIN GLASS FRANCE (FR) 2023-10-05 WO disclosed
EP-3601258-B1 SUBSTITUTED ISOQUIONLINE DERIVATIVES AS IMMUNOMUDULATORS BRISTOL MYERS SQUIBB CO (US) 2023-08-30 EP disclosed
EP-3856188-B1 AMINOPYRIMIDINE COMPOUND CARDURION PHARMACEUTICALS INC (US) 2023-06-21 EP disclosed
EP-4161522-A1 PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF CELLULAR PROLIFERATIVE DISORDERS Merck Sharp & Dohme LLC (US) 2023-04-12 EP disclosed
CN-113979981-B Sulfhydryl response type dealkalized site capture reagent and application 天津医科大学 2023-04-07 CN disclosed
EP-3507284-B1 BIARYL COMPOUNDS USEFUL AS IMMUNOMODULATORS BRISTOL MYERS SQUIBB CO (US) 2022-05-25 EP disclosed
WO-2008037784-A1 QUINOLINONE DERIVATIVES TIBOTEC PHARMACEUTICALS LTD. (IE) 2008-04-03 WO disclosed
US-20070088170-A1 Novel compounds PRONOVA BIOPHARMA NORGE AS (NO) 2007-04-19 US disclosed
US-20070088170-A1 Novel compounds PRONOVA BIOPHARMA NORGE AS (NO) 2007-04-19 US disclosed
CN-1935860-A Method for producing ethylene-vinyl acetate copolymer chlorinated resin by acid phase process UNIV HEFEI POLYTECHNIC (CN) 2007-03-28 CN disclosed
CN-1821323-A Water dispersion chromium-free single component silicon steel insulation paint and its preparing method AOER CHEMICAL CO LTD WUXI CITY (CN) 2006-08-23 CN disclosed
CN-1137247-C Polymer-type efficient demulsifier for emulsion of crude oil and its synthesizing process 东南大学 2004-02-04 CN disclosed
CN-1118495-C Water-dispersible polymer and coating composition containing the same DEXTER CORP (US) 2003-08-20 CN disclosed
CN-1317544-A Polymer-type efficient demulsifier for emulsion of crude oil and its synthesizing process UNIV DONGNAN (CN) 2001-10-17 CN disclosed
CN-1211261-A Water-dispersible polymer and coating composition containing the same DEXTER CORP (US) 1999-03-17 CN disclosed
CN-1039379-A PRESSURE-SENSITIVE ADHESIVE SHEETS KANSAI PAINT CO LTD (JP) 1990-02-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070088170-A1 Novel compounds FFAR2, GPR119, ALOX12 TSHR 2384/4885HCAR2 40/4885CA12 2868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.