Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | HTR2B | P41595 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21767388 | 1.00 | PDE10A (0.42) | PDE10AHTR2CHTR2BHTR2AKCNH2 | |
| SCHEMBL21767380 | 1.00 | PDE10A (0.42) | PDE10AHTR2CHTR2BHTR2AKCNH2 | |
| SCHEMBL21767378 | 1.00 | PDE10A (0.42) | PDE10AHTR2CHTR2BHTR2AKCNH2 | |
| SCHEMBL4253493 | 0.81 | PDE10A (0.45) | PDE10AHTR2CHTR2BHTR2AKCNH2 | |
| SCHEMBL20153763 | 0.73 | PDE10A (0.54) | PDE10AHTR2CHTR2BHTR2A | |
| SCHEMBL16668842 | 0.73 | PDE10A (0.38) | PDE10A | |
| SCHEMBL22397485 | 0.72 | ALOX5 (0.33) | HTR2CHTR2BHTR2AKCNH2ALOX5 | |
| SCHEMBL7556092 | 0.71 | PDE10A (0.52) | PDE10A | |
| SCHEMBL19365307 | 0.71 | ALOX5 (0.33) | HTR2CHTR2BHTR2AKCNH2ALOX5 | |
| SCHEMBL8039039 | 0.70 | GSK3B (0.39) | PDE10AHTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878533-A | Inhibition of αvβ6 integrin | 莫菲克医疗股份有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-112805001-B | Inhibition of αvβ6 integrin | 莫菲克医疗股份有限公司 | 2024-07-23 | — | — | CN | disclosed |