SCHEMBL3107248

SCHEMBL3107248

Oc1cccc(-c2c3nc(cc4ccc(cc5nc(cc6ccc2[nH]6)C=C5)[nH]4)C=C3)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.64
▸ STAT1 P42224 1/20 0.64
▸ MGAM O43451 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ SI P14410 1/20 0.39
▸ MGAM2 Q2M2H8 1/20 0.39
▸ PTPN1 P18031 1/20 0.39
▸ AURKA O14965 1/20 0.37
▸ RIPK1 Q13546 1/20 0.36
▸ MAPK13 O15264 1/20 0.36
▸ RAF1 P04049 1/20 0.36
▸ BRAF P15056 1/20 0.36
▸ MAPK12 P53778 1/20 0.36
▸ MAPK11 Q15759 1/20 0.36
▸ MAPK14 Q16539 1/20 0.36
▸ BRDT Q58F21 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ RXFP1 Q9HBX9 1/20 0.36
▸ PARP1 P09874 1/20 0.36
▸ HSD17B1 P14061 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL584789 0.97 STAT3 (0.67) STAT3STAT1MGAMGAASI
SCHEMBL29403134 0.85 STAT3 (0.64) STAT3STAT1TOP1TERTCYCS
SCHEMBL3352961 0.85 STAT3 (0.64) STAT3STAT1TOP1TERTCYCS
SCHEMBL473158 0.85 STAT3 (0.86) STAT3STAT1TOP1TERTCYCS
SCHEMBL6803313 0.85 STAT3 (0.63) STAT3STAT1TOP1TERTCYCS
SCHEMBL30753635 0.85 STAT3 (0.86) STAT3STAT1TOP1TERTCYCS
SCHEMBL6033674 0.85 STAT3 (0.64) STAT3STAT1TOP1TERTCYCS
SCHEMBL29402399 0.84 STAT3 (0.63) STAT3STAT1TOP1TERTCYCS
SCHEMBL28459011 0.84 STAT3 (0.63) STAT3STAT1TOP1TERTCYCS
SCHEMBL14973450 0.84 STAT3 (0.63) STAT3STAT1TOP1TERTCYCS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119223945-A High-temperature Daqu liquor identification method based on porphyrin catalyst quasi-peroxidase activity oxidation TMB color change 中南民族大学 2024-12-31 — — CN claimed
CN-118555971-A Amorphous photosensitive particles, methods of making and methods of using the same 马里兰大学帕克分校 2024-08-27 — — CN claimed
CN-112940268-B Interface in-situ growth metal-organic framework material and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-04-12 — — CN claimed
CN-112940268-A Interface in-situ growth metal-organic framework material and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2021-06-11 — — CN claimed
US-9211283-B2 Nanoparticle carrier systems based on human serum albumin for photodynamic therapy BIOLITEC PHARMA MARKETING LTD (MY) 2015-12-15 — — US claimed
CN-1605026-A Electrode for active oxygen species and sensor using the electrode MAKOTO YUASA (JP) 2005-04-06 — — CN claimed
EP-1263761-B1 COMPOUNDS FOR PDT BIOLITEC PHARMA MARKETING LTD (MY) 2004-12-01 — — EP claimed
EP-0337601-B1 PORPHYRINS AND MEDICAMENTS FOR CANCER TREATMENT SCOTIA HOLDINGS PLC (GB) 1993-05-05 — — EP claimed
CN-119223945-A High-temperature Daqu liquor identification method based on porphyrin catalyst quasi-peroxidase activity oxidation TMB color change 中南民族大学 2024-12-31 — — CN disclosed
CN-118555971-A Amorphous photosensitive particles, methods of making and methods of using the same 马里兰大学帕克分校 2024-08-27 — — CN disclosed
CN-109922834-B Porphyrin compounds and compositions for the treatment of cancer 良药治疗公司 2022-09-23 — — CN disclosed
CN-112940268-B Interface in-situ growth metal-organic framework material and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-04-12 — — CN disclosed
CN-112940268-A Interface in-situ growth metal-organic framework material and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2021-06-11 — — CN disclosed
EP-2509633-A2 NANOPARTICLE CARRIER SYSTEMS BASED ON POLY(DL-LACTIC-CO-GLYCOLIC ACID) (PLGA) FOR PHOTODYNAMIC THERAPY (PDT) CeramOptec GmbH (DE) 2012-10-17 — — EP disclosed
CN-102256622-A Calciumphosphate-based nanoparticles as carrier-systems for photodynamic therapy BIOLITEC AG 2011-11-23 — — CN disclosed
US-20100256136-A1 Method for Enhancing Pdt Efficacy Using a Tyrosine Kinase Inhibitor NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-10-07 — — US disclosed
CN-1605026-A Electrode for active oxygen species and sensor using the electrode MAKOTO YUASA (JP) 2005-04-06 — — CN disclosed
US-20030212052-A1 Use of ursdeoxycholic acid for potentiation of the phototoxic effect of photodynamic therapy NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-11-13 — — US disclosed
EP-0820305-A2 CANCER TREATMENT BY PHOTODYNAMIC THERAPY, IN COMBINATION WITH AN IMMUNOADJUVANT Wound Healing of Oklahoma (US) 1998-01-28 — — EP disclosed
WO-1996031237-A2 CANCER TREATMENT BY PHOTODYNAMIC THERAPY, IN COMBINATION WITH AN IMMUNOADJUVANT WOUND HEALING OF OKLAHOMA (US) 1996-10-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256136-A1 Method for Enhancing Pdt Efficacy Using a Tyrosine Kinase Inhibitor UROD, SLC7A1, TAP2 STAT3 967/4885STAT1 1433/4885MGAM 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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