SCHEMBL6033674

SCHEMBL6033674

Sc1cccc(-c2c3nc(cc4ccc(cc5nc(cc6ccc2[nH]6)C=C5)[nH]4)C=C3)c1

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.64
▸ STAT1 P42224 1/20 0.64
▸ TERT O14746 5/20 0.35
▸ TOP1 P11387 4/20 0.33
▸ CYCS P99999 3/20 0.32
▸ IDO1 P14902 1/20 0.32
▸ ENPP2 Q13822 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30753635 0.85 STAT3 (0.86) STAT3STAT1TERTTOP1CYCS
SCHEMBL473158 0.85 STAT3 (0.86) STAT3STAT1TERTTOP1CYCS
SCHEMBL3107248 0.85 STAT3 (0.64) STAT3STAT1TERTTOP1CYCS
SCHEMBL1275381 0.84 STAT3 (0.84) STAT3STAT1TERTTOP1CYCS
SCHEMBL2563180 0.82 STAT3 (0.91) STAT3STAT1TERTTOP1CYCS
SCHEMBL5918856 0.82 TERT (0.49) STAT3STAT1TERTTOP1CYCS
SCHEMBL584789 0.82 STAT3 (0.67) STAT3STAT1TERTTOP1CYCS
SCHEMBL7913296 0.81 STAT3 (0.60) STAT3STAT1TERTTOP1CYCS
SCHEMBL2948398 0.81 STAT3 (0.60) STAT3STAT1
SCHEMBL31127547 0.81 STAT3 (0.89) STAT3STAT1TERTTOP1CYCS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1457773-B1 ELECTRODE FOR ACTIVE OXYGEN SPECIES AND SENSOR USING THE ELECTRODE YUASA MAKOTO (JP) 2006-05-03 — — EP claimed
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