Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29342594 | 1.00 | POLB (0.47) | POLBNPC1CYP2C9RAB9ACNR2 | |
| SCHEMBL13477414 | 0.87 | PARP1 (0.47) | CNR2KMT2AKIF11ACHE | |
| SCHEMBL2060134 | 0.83 | CNR2 (0.52) | CNR2KIF11PIN1ACHE | |
| SCHEMBL395978 | 0.82 | PIN1 (0.54) | POLBCNR2KMT2ASMN1; SMN2NPSR1 | |
| Benzene SCHEMBL28258998 | 0.82 | PIN1 (0.54) | POLBCNR2KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL3923273 | 0.81 | CNR2 (0.51) | POLBCNR2PIN1 | |
| SCHEMBL421400 | 0.80 | CNR2 (0.47) | CNR2KMT2ASMN1; SMN2 | |
| SCHEMBL5216184 | 0.80 | NPSR1 (0.49) | POLBCNR2KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL12021018 | 0.80 | CNR2 (0.47) | CNR2NPSR1PIN1 | |
| SCHEMBL29701153 | 0.80 | CNR2 (0.47) | CNR2KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4648762-A2 | PPARG MODULATORS | University of Florida Research Foundation, Incorporated (US) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024151519-A2 | PPARG MODULATORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATIN, INCORPORATED (US) | 2024-07-18 | — | — | WO | disclosed |