SCHEMBL31073184

SCHEMBL31073184

Cn1c2cc(C3(O)CCN(C(=O)OC(C)(C)C)CC3)ccc2c(=O)n1C1CCC(=O)NC1=O

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 14/20 0.45
▸ CRBN Q96SW2 14/20 0.45
▸ PRKCG P05129 1/20 0.36
▸ PRKCB P05771 1/20 0.36
▸ PRKCA P17252 1/20 0.36
▸ PRKCH P24723 1/20 0.36
▸ PRKCE Q02156 1/20 0.36
▸ PRKCD Q05655 1/20 0.36
▸ KMT2A Q03164 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ THRB P10828 1/20 0.35
▸ CCR5 P51681 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31073375 0.86 HRH3 (0.33) DDB1CRBNKMT2A
SCHEMBL31073033 0.82 CRBN (0.38) DDB1CRBNKMT2A
SCHEMBL31073232 0.80 CRBN (0.46) DDB1CRBN
SCHEMBL27157361 0.79 CRBN (0.55) DDB1CRBN
SCHEMBL30036087 0.79 CRBN (0.55) DDB1CRBN
SCHEMBL31433939 0.79 DDB1 (0.70) DDB1CRBN
SCHEMBL23306591 0.77 CRBN (0.54) DDB1CRBN
SCHEMBL31072968 0.77 CRBN (0.54) DDB1CRBN
SCHEMBL29712444 0.77 CRBN (0.54) DDB1CRBN
SCHEMBL27039438 0.75 CRBN (0.62) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024173646-A1 CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. (US) 2024-08-22 — — WO disclosed
Send feedback