SCHEMBL31433939

SCHEMBL31433939

Cn1nc(C2CCC(=O)NC2=O)c2ccc(C3(O)CCN(C(=O)OC(C)(C)C)CC3)cc21

nearest known ligand 0.70

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 19/20 0.70
▸ CRBN Q96SW2 19/20 0.70
▸ CNR1 P21554 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30731916 0.92 DDB1 (0.65) DDB1CRBNCNR1
SCHEMBL26924976 0.92 DDB1 (0.65) DDB1CRBNCNR1
SCHEMBL31433768 0.91 DDB1 (0.69) DDB1CRBN
SCHEMBL30830903 0.85 DDB1 (0.69) DDB1CRBN
SCHEMBL23540247 0.85 DDB1 (0.75) DDB1CRBNCNR1
SCHEMBL31236425 0.85 CRBN (0.75) DDB1CRBN
SCHEMBL30776681 0.85 DDB1 (0.75) DDB1CRBN
SCHEMBL30706226 0.85 DDB1 (0.75) DDB1CRBN
SCHEMBL30026749 0.85 DDB1 (0.75) DDB1CRBNCNR1
SCHEMBL30768785 0.85 DDB1 (0.75) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025050016-A1 TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2025-03-06 — — WO disclosed
Send feedback