Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 10/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.41 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22006726 | 0.82 | DDB1 (0.54) | DDB1CRBNNAMPT | |
| SCHEMBL20234368 | 0.82 | DDB1 (0.51) | DDB1CRBN | |
| SCHEMBL25036448 | 0.81 | CDK7 (0.45) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL31073337 | 0.80 | DDB1 (0.42) | DDB1CRBNNAMPT | |
| SCHEMBL30493301 | 0.79 | CRBN (0.49) | DDB1CRBN | |
| SCHEMBL31073284 | 0.78 | JAK1 (0.45) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL20046320 | 0.78 | CRBN (0.54) | DDB1CRBNJAK1BRD4PDK4 | |
| SCHEMBL29367280 | 0.78 | CRBN (0.54) | DDB1CRBNJAK1BRD4PDK4 | |
| SCHEMBL30274113 | 0.78 | CDK7 (0.43) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL25224393 | 0.77 | NAMPT (0.46) | DDB1CRBNCDK7CDK13CDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173646-A1 | CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |