Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 14/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 14/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GRAMD1A | Q96CP6 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20234368 | 0.85 | DDB1 (0.51) | DDB1CRBN | |
| SCHEMBL22006726 | 0.85 | DDB1 (0.54) | DDB1CRBNNAMPTKDM4EMAPT | |
| SCHEMBL30493301 | 0.82 | CRBN (0.49) | DDB1CRBN | |
| SCHEMBL31073090 | 0.81 | CRBN (0.39) | DDB1CRBN | |
| SCHEMBL31073198 | 0.80 | DDB1 (0.43) | DDB1CRBNNAMPT | |
| SCHEMBL31073232 | 0.78 | CRBN (0.46) | DDB1CRBNNAMPT | |
| SCHEMBL25931211 | 0.78 | DDB1 (0.54) | DDB1CRBN | |
| SCHEMBL27157361 | 0.77 | CRBN (0.55) | DDB1CRBN | |
| SCHEMBL30036087 | 0.77 | CRBN (0.55) | DDB1CRBN | |
| SCHEMBL23306591 | 0.75 | CRBN (0.54) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173646-A1 | CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |