Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 5/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31072975 | 1.00 | MAPT (0.50) | MAPTPOLBRAB9APTGS1SLC6A2 | |
| SCHEMBL31073430 | 0.88 | POLB (0.48) | MAPTPOLBRAB9ACHRNB2CHRNB4 | |
| SCHEMBL31073373 | 0.88 | POLB (0.48) | MAPTPOLBRAB9ACHRNB2CHRNB4 | |
| SCHEMBL31073083 | 0.87 | POLB (0.47) | MAPTPOLBRAB9ACHRNB2CHRNB4 | |
| SCHEMBL31073487 | 0.87 | POLB (0.47) | MAPTPOLBRAB9ACHRNB2CHRNB4 | |
| SCHEMBL31072986 | 0.84 | KCNH2 (0.41) | FFAR4ACACBKCNH2 | |
| SCHEMBL31073339 | 0.82 | MAPT (0.55) | MAPTPOLBRAB9APTGS1SLC6A2 | |
| SCHEMBL31073259 | 0.81 | MAPT (0.49) | MAPTPOLBRAB9ACHRNB2CHRNB4 | |
| SCHEMBL17654192 | 0.81 | MAPT (0.63) | MAPTPOLBRAB9APTGS1SLC6A2 | |
| SCHEMBL31607956 | 0.79 | POLB (0.51) | MAPTPOLBRAB9APTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173646-A1 | CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |