Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | TGM2 | P21980 | 3/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31073430 | 0.83 | POLB (0.48) | MAPTPOLBSMN1; SMN2RAB9ACHRNB2 | |
| SCHEMBL31073373 | 0.83 | POLB (0.48) | MAPTPOLBSMN1; SMN2RAB9ACHRNB2 | |
| SCHEMBL31073002 | 0.83 | GCK (0.38) | GPR119 | |
| SCHEMBL31073083 | 0.83 | POLB (0.47) | MAPTPOLBSMN1; SMN2RAB9ACHRNB2 | |
| SCHEMBL31073487 | 0.83 | POLB (0.47) | MAPTPOLBSMN1; SMN2RAB9ACHRNB2 | |
| SCHEMBL31073252 | 0.81 | MAPT (0.50) | MAPTPOLBSMN1; SMN2RAB9ACHRNB2 | |
| SCHEMBL31072975 | 0.81 | MAPT (0.50) | MAPTPOLBSMN1; SMN2RAB9ACHRNB2 | |
| SCHEMBL31073444 | 0.78 | MAPT (0.44) | MAPTPOLBSMN1; SMN2RAB9ACHRNB2 | |
| SCHEMBL4696975 | 0.75 | MAPT (0.67) | MAPTPOLBSMN1; SMN2RAB9ACHRNB2 | |
| SCHEMBL31607956 | 0.74 | POLB (0.51) | MAPTPOLBSMN1; SMN2RAB9ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173646-A1 | CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |