Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20676972 | 1.00 | MAPT (0.74) | MAPTPOLBRAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL29435521 | 0.87 | MAPT (0.97) | MAPTPOLBRAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL15141576 | 0.87 | MAPT (0.97) | MAPTPOLBRAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL3539759 | 0.87 | MAPT (0.90) | MAPTPOLBRAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL2722856 | 0.85 | MAPT (1.00) | MAPTPOLBRAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL29437410 | 0.85 | MAPT (1.00) | MAPTPOLBRAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL2726097 | 0.83 | MAPT (0.72) | MAPTPOLBRAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL521907 | 0.83 | MAPT (0.72) | MAPTPOLBRAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL29349693 | 0.83 | MAPT (0.72) | MAPTPOLBRAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL1392957 | 0.83 | MAPT (0.72) | MAPTPOLBRAB9ASMN1; SMN2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173646-A1 | CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |