SCHEMBL31073480

SCHEMBL31073480

O=C1CCC(n2ncc3cc(C4(O)CCNCC4)ccc3c2=O)C(=O)N1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 18/20 0.51
▸ DDB1 Q16531 14/20 0.51
▸ IKZF3 Q9UKT9 3/20 0.35
▸ ALDH1A1 P00352 1/20 0.34
▸ CHRM2 P08172 1/20 0.34
▸ OPRM1 P35372 1/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31073232 0.81 CRBN (0.46) CRBNDDB1
SCHEMBL26248314 0.81 CRBN (0.56) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL24861073 0.80 CRBN (0.53) CRBNDDB1IKZF3ALDH1A1CHRM2
Hydrochloric Acid SCHEMBL31331017 0.79 CRBN (0.52) CRBNDDB1
SCHEMBL24861377 0.79 CRBN (0.56) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL26248254 0.79 CRBN (0.56) CRBNDDB1IKZF3
SCHEMBL26247581 0.79 CRBN (0.56) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL31538742 0.78 CRBN (0.53) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL24861081 0.76 CRBN (0.53) CRBNDDB1
SCHEMBL26250141 0.76 CRBN (0.72) CRBNDDB1IKZF3ALDH1A1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024173646-A1 CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. (US) 2024-08-22 — — WO disclosed
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