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Sugi Predict / Compounds / SCHEMBL31073545

SCHEMBL31073545

SCHEMBL31073545

N=C(N)NCCC[C@H](NC(=O)[C@@H](N)Cc1ccc(-c2ccccc2)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 7/20 0.55
▸ NPBWR1 P48145 2/20 0.52
▸ UTS2R Q9UKP6 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29511074 0.96 GHSR (0.59) GHSR
SCHEMBL30029017 0.96 GHSR (0.59) GHSR
SCHEMBL31661149 0.95 GHSR (0.61) GHSR
SCHEMBL30919239 0.94 GHSR (0.61) GHSRNPBWR1
SCHEMBL30878117 0.94 GHSR (0.56) GHSR
SCHEMBL29483773 0.94 GHSR (0.56) GHSRNPBWR1UTS2R
SCHEMBL29483771 0.94 GHSR (0.56) GHSRNPBWR1UTS2R
SCHEMBL29483772 0.94 GHSR (0.56) GHSRNPBWR1UTS2R
SCHEMBL31593359 0.92 GHSR (0.56) GHSRNPBWR1UTS2R
SCHEMBL29790169 0.92 GHSR (0.56) GHSRNPBWR1UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665374-A1 METHODS OF PREVENTING AND/OR TREATING SIDE EFFECTS ASSOCIATED WITH ANTI-CANCER AGENTS USING NON-NATURALLY OCCURRING MELANOCORTIN ANALOGS WITH ANTI-GDF-15 ANTIBODIES Endevica Bio, Inc. (US) 2025-12-24 — — EP disclosed
WO-2024173905-A1 METHODS OF PREVENTING AND/OR TREATING SIDE EFFECTS ASSOCIATED WITH ANTI-CANCER AGENTS USING NON-NATURALLY OCCURRING MELANOCORTIN ANALOGS WITH ANTI-GDF-15 ANTIBODIES ENDEVICA BIO, INC. (US) 2024-08-22 — — WO disclosed
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