SCHEMBL31074737

SCHEMBL31074737

C[C@H](N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 13/20 0.46
▸ NPY1R P25929 9/20 0.46
▸ NPY5R Q15761 7/20 0.46
▸ NPY2R P49146 5/20 0.46
▸ GNPAT O15228 1/20 0.46
▸ APLNR P35414 1/20 0.44
▸ GHSR Q92847 1/20 0.42
▸ FNTA P49354 3/20 0.42
▸ FNTB P49356 3/20 0.42
▸ PGGT1B P53609 3/20 0.42
▸ C5AR1 P21730 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30264773 0.94 APLNR (0.47) NPY4RNPY1RNPY5RNPY2RAPLNR
SCHEMBL31267994 0.94 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2RAPLNR
SCHEMBL29420164 0.91 NPY4R (0.47) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL30152128 0.91 NPY4R (0.47) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL30475874 0.91 NPY4R (0.49) NPY4RNPY1RNPY5RNPY2RGHSR
SCHEMBL29958548 0.91 NPY4R (0.49) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL29482503 0.90 FNTA (0.51) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL29482469 0.90 NPY4R (0.45) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL29511195 0.90 FNTA (0.51) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL30475873 0.90 NPY4R (0.45) NPY4RNPY1RNPY5RNPY2RGNPAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240287154-A1 MC3R AGONIST PEPTIDES COURAGE THERAPEUTICS, INC. 2024-08-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287154-A1 MC3R AGONIST PEPTIDES MC3R, MC4R, MC1R NPY4R 15/4885NPY1R 19/4885NPY5R 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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