Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 8/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL31075258 | 0.87 | ESR2 (0.53) | ESR2NR1H2KDM1ATUBB4ATUBB | |
| SCHEMBL22993097 | 0.83 | HDAC1 (0.46) | HPGDSMN1; SMN2ALDH1A1LMNAESR2 | |
| SCHEMBL29407328 | 0.83 | HDAC1 (0.46) | HPGDSMN1; SMN2ALDH1A1LMNAESR2 | |
| SCHEMBL14768550 | 0.79 | ESR2 (0.70) | HPGDESR2NR1H2MAPK1ADORA1 | |
| SCHEMBL13945301 | 0.79 | KDM1A (0.52) | ALDH1A1ESR2NR1H2KDM1ATUBB4A | |
| SCHEMBL5173084 | 0.78 | ESR2 (0.43) | HPGDSMN1; SMN2ALDH1A1LMNAESR2 | |
| SCHEMBL31337577 | 0.77 | ESR2 (0.65) | HPGDALDH1A1ESR2NR1H2MAPK1 | |
| SCHEMBL30583396 | 0.77 | ESR2 (0.65) | HPGDALDH1A1ESR2NR1H2MAPK1 | |
| Hydrochloric Acid SCHEMBL29697689 | 0.77 | HDAC1 (0.43) | HPGDSMN1; SMN2ALDH1A1LMNAESR2 | |
| SCHEMBL31075231 | 0.76 | ADORA1 (0.48) | HPGDSMN1; SMN2ALDH1A1LMNAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665330-A1 | PLASMA KALLIKREIN INHIBITORS | Merck Sharp & Dohme LLC (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173196-A1 | PLASMA KALLIKREIN INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-08-22 | — | — | WO | disclosed |