SCHEMBL31337577

SCHEMBL31337577

CCOC(=O)c1ccc2c(c1)CCN(C(=O)OC(C)(C)C)C2

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.65
NR1H2 P55055 1/20 0.57
HDAC6 Q9UBN7 3/20 0.51
HDAC8 Q9BY41 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
ADORA1 P30542 1/20 0.49
ATM Q13315 1/20 0.44
MAPK1 P28482 3/20 0.43
ALDH1A1 P00352 3/20 0.43
TSHR P16473 2/20 0.43
HPGD P15428 2/20 0.43
SRD5A1 P18405 1/20 0.43
SRD5A2 P31213 1/20 0.43
ESR1 P03372 1/20 0.43
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
HSD17B10 Q99714 1/20 0.42
ABHD6 Q9BV23 1/20 0.42
HDAC1 Q13547 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30583396 1.00 ESR2 (0.65) ESR2NR1H2HDAC6HDAC8MEN1
SCHEMBL30583454 0.95 NR1H2 (0.63) ESR2NR1H2HDAC6HDAC8MEN1
SCHEMBL1648607 0.95 NR1H2 (0.63) ESR2NR1H2HDAC6HDAC8MEN1
SCHEMBL1650181 0.90 ESR2 (0.50) ESR2NR1H2HDAC6HDAC8MEN1
SCHEMBL1648620 0.89 NR1H2 (0.55) ESR2NR1H2HDAC6MEN1KMT2A
SCHEMBL30301758 0.87 ESR2 (0.69) ESR2NR1H2HDAC6HDAC8MAPK1
SCHEMBL3024823 0.87 ESR2 (0.69) ESR2NR1H2HDAC6HDAC8MAPK1
SCHEMBL19643324 0.85 ESR2 (0.57) ESR2NR1H2HDAC6HDAC8MEN1
SCHEMBL19643328 0.85 ESR2 (0.57) ESR2NR1H2HDAC6HDAC8MEN1
SCHEMBL19643329 0.85 ESR2 (0.57) ESR2NR1H2HDAC6HDAC8MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119365479-A Conjugates comprising Toll-like receptor agonists 慕宝盛科生物医药(上海)有限公司 2025-01-24 CN disclosed