Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31075206 | 0.86 | EGLN1 (0.43) | PGRADORA3PTGS1SLC6A2KLKB1 | |
| SCHEMBL553163 | 0.83 | KLKB1 (0.52) | ALDH1A1KLKB1MAPTLMNAGAA | |
| SCHEMBL25911754 | 0.76 | ITK (0.46) | ALDH1A1KLKB1MAPTLMNAGAA | |
| SCHEMBL16827699 | 0.72 | CREBBP (0.51) | ALDH1A1MAPTLMNAGAAS1PR3 | |
| SCHEMBL23212254 | 0.72 | CYP1A2 (0.55) | ALDH1A1KLKB1MAPTLMNAGAA | |
| SCHEMBL12913218 | 0.72 | CYP1A2 (0.55) | ALDH1A1KLKB1MAPTLMNAGAA | |
| SCHEMBL949168 | 0.72 | CYP1A2 (0.55) | ALDH1A1KLKB1MAPTLMNAGAA | |
| SCHEMBL5106095 | 0.71 | CYP1A2 (0.47) | ALDH1A1MAPTLMNAGAANPC1 | |
| SCHEMBL30825007 | 0.70 | NPY2R (0.41) | ALDH1A1KLKB1MAPTLMNAGAA | |
| SCHEMBL25911826 | 0.70 | CYP1A2 (0.45) | ALDH1A1KLKB1MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665330-A1 | PLASMA KALLIKREIN INHIBITORS | Merck Sharp & Dohme LLC (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173196-A1 | PLASMA KALLIKREIN INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-08-22 | — | — | WO | disclosed |