SCHEMBL949168

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12913218	1.00	CYP1A2 (0.55)	CYP1A2CYP3A4GABRA1GABRB2CYP11B1
	SCHEMBL23212254	1.00	CYP1A2 (0.55)	CYP1A2CYP3A4GABRA1GABRB2CYP11B1
	SCHEMBL5106095	0.88	CYP1A2 (0.47)	CYP1A2CYP3A4GABRA1GABRB2CYP11B1
	SCHEMBL27919054	0.87	GABRB2 (0.44)	CYP1A2CYP3A4GABRA1GABRB2CYP11B1
	SCHEMBL25911743	0.86	CYP1A2 (0.46)	CYP1A2CYP3A4GABRA1GABRB2CYP11B1
	SCHEMBL25911742	0.86	CYP1A2 (0.46)	CYP1A2CYP3A4GABRA1GABRB2CYP11B1
	SCHEMBL25911754	0.86	ITK (0.46)	CYP1A2CYP3A4GABRA1GABRB2CYP11B1
	SCHEMBL25911583	0.86	HTT (0.47)	CYP1A2CYP3A4GABRA1GABRB2CYP11B1
	SCHEMBL31043465	0.86	HTT (0.47)	CYP1A2CYP3A4GABRA1GABRB2CYP11B1
	SCHEMBL31502175	0.86	HTT (0.47)	CYP1A2CYP3A4GABRA1GABRB2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.