Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 6/20 | 0.36 |
| ▸ | ITGB6 | P18564 | 6/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31076085 | 0.92 | ITGAV (0.36) | ITGAVITGB6USP30GPR119NR1D1 | |
| SCHEMBL31075653 | 0.91 | GPR119 (0.38) | ITGAVITGB6USP30GPR119NR1D1 | |
| SCHEMBL31075702 | 0.90 | ITGAV (0.38) | ITGAVITGB6USP30GPR119NR1D1 | |
| SCHEMBL31075940 | 0.90 | ITGAV (0.38) | ITGAVITGB6USP30GPR119NR1D1 | |
| SCHEMBL31075714 | 0.90 | ITGAV (0.38) | ITGAVITGB6USP30GPR119NR1D1 | |
| SCHEMBL31076169 | 0.90 | ITGAV (0.38) | ITGAVITGB6USP30GPR119NR1D1 | |
| SCHEMBL31075867 | 0.89 | ITGAV (0.40) | ITGAVITGB6USP30GPR119NR1D1 | |
| SCHEMBL31075948 | 0.88 | ITGAV (0.38) | ITGAVITGB6USP30GPR119NR1D1 | |
| SCHEMBL31075984 | 0.88 | ITGAV (0.36) | ITGAVITGB6USP30GPR119NR1D1 | |
| SCHEMBL31075811 | 0.88 | USP30 (0.37) | ITGAVITGB6USP30GPR119NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665458-A1 | INHIBITING ALPHA V BETA8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173572-A1 | INHIBITING α vβ8 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2024-08-22 | — | — | WO | disclosed |