Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4274661 | 0.79 | KDM4E (0.43) | KDM4EPOLBCYP2C9MAPTALDH1A1 | |
| SCHEMBL25248214 | 0.76 | MAPT (0.43) | KDM4EPOLBCYP2C9MAPTALDH1A1 | |
| SCHEMBL4551498 | 0.75 | GLA (0.44) | KDM4ECYP2C9MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8895875 | 0.73 | KDM4E (0.35) | KDM4EPOLBCYP2C9MAPTALDH1A1 | |
| SCHEMBL26137720 | 0.73 | DPP4 (0.32) | — | |
| SCHEMBL23850649 | 0.71 | MEN1 (0.41) | POLBCYP2C9MAPTALDH1A1HPGD | |
| SCHEMBL30620176 | 0.71 | KMT2A (0.43) | POLBSMN1; SMN2HPGDKMT2ATDP1 | |
| SCHEMBL15490071 | 0.71 | KMT2A (0.43) | POLBSMN1; SMN2HPGDKMT2ATDP1 | |
| SCHEMBL12985044 | 0.70 | MAPT (0.42) | KDM4ECYP2C9MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5357828 | 0.70 | DAO (0.43) | KDM4ECYP2C9MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665458-A1 | INHIBITING ALPHA V BETA8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173572-A1 | INHIBITING α vβ8 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2024-08-22 | — | — | WO | disclosed |