Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4274661 | 0.78 | KDM4E (0.43) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL31075813 | 0.73 | KDM4E (0.41) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4551498 | 0.71 | GLA (0.44) | KDM4EMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8894054 | 0.71 | SLC7A5 (0.39) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL25248214 | 0.70 | MAPT (0.43) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22469077 | 0.68 | USP2 (0.50) | KDM4EMAPTALDH1A1HPGDLMNA | |
| SCHEMBL22469075 | 0.68 | USP2 (0.50) | KDM4EMAPTALDH1A1HPGDLMNA | |
| SCHEMBL31287306 | 0.68 | USP2 (0.50) | KDM4EMAPTALDH1A1HPGDLMNA | |
| SCHEMBL16110330 | 0.67 | FFAR1 (0.47) | KDM4EMAPTALDH1A1L3MBTL1GAA | |
| SCHEMBL24821192 | 0.66 | NLRP3 (0.40) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997026248-A1 | SUBSTITUTED N-ARYL NITROGEN HETEROCYCLIC COMPOUNDS AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-24 | — | — | WO | disclosed |