Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 13/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20025188 | 1.00 | MPO (0.37) | MPOITGAVITGB6FGFR4GPR119 | |
| SCHEMBL26314452 | 0.99 | MPO (0.37) | MPOITGAVITGB6FGFR4GPR119 | |
| SCHEMBL29416391 | 0.97 | MPO (0.38) | MPOITGAVITGB6FGFR4GPR119 | |
| SCHEMBL20158202 | 0.97 | MPO (0.38) | MPOITGAVITGB6FGFR4GPR119 | |
| SCHEMBL20153411 | 0.94 | MPO (0.37) | MPOITGAVITGB6FGFR4GPR119 | |
| SCHEMBL29860313 | 0.94 | MPO (0.37) | MPOITGAVITGB6FGFR4GPR119 | |
| SCHEMBL20158352 | 0.93 | MPO (0.39) | MPOFGFR4BRD4NPC1RAB9A | |
| SCHEMBL20025208 | 0.91 | MPO (0.37) | MPOITGAVITGB6FGFR4GPR119 | |
| SCHEMBL14380644 | 0.90 | MPO (0.38) | MPOITGAVITGB6FGFR4GPR119 | |
| SCHEMBL21328581 | 0.89 | MPO (0.39) | MPOITGAVITGB6FGFR4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665458-A1 | INHIBITING ALPHA V BETA8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173572-A1 | INHIBITING α vβ8 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2024-08-22 | — | — | WO | disclosed |