Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19990923 | 0.87 | USP30 (0.49) | EPHX1USP30CYP2C9HSD11B1ALDH1A1 | |
| SCHEMBL13712553 | 0.87 | USP30 (0.49) | EPHX1USP30CYP2C9HSD11B1ALDH1A1 | |
| SCHEMBL25237250 | 0.85 | EPHX1 (0.52) | EPHX1USP30CYP2C9HSD11B1ALDH1A1 | |
| SCHEMBL18556969 | 0.85 | EPHX1 (0.52) | EPHX1USP30CYP2C9HSD11B1ALDH1A1 | |
| SCHEMBL13696753 | 0.85 | EPHX1 (0.52) | EPHX1USP30CYP2C9HSD11B1ALDH1A1 | |
| SCHEMBL23555643 | 0.84 | EPHX1 (0.51) | EPHX1USP30CYP2C9HSD11B1ALDH1A1 | |
| SCHEMBL31075790 | 0.84 | EPHX1 (0.46) | EPHX1USP30CYP2C9HSD11B1ALDH1A1 | |
| SCHEMBL31421132 | 0.83 | EPHX1 (0.53) | EPHX1USP30CYP2C9HSD11B1ALDH1A1 | |
| SCHEMBL24033437 | 0.82 | EPHX1 (0.49) | EPHX1USP30CYP2C9HSD11B1ALDH1A1 | |
| SCHEMBL30999407 | 0.82 | EPHX1 (0.49) | EPHX1USP30CYP2C9HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665458-A1 | INHIBITING ALPHA V BETA8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173572-A1 | INHIBITING α vβ8 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2024-08-22 | — | — | WO | disclosed |