SCHEMBL31076390

SCHEMBL31076390

CC(C)(C)OC(=O)N1CCOC(Cc2cccc(Cl)c2-c2ccns2)C1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHA2 P29317 4/20 0.42
ERBB2 P04626 1/20 0.41
EPHB4 P54760 1/20 0.41
MAPT P10636 1/20 0.40
STS P08842 1/20 0.36
RET P07949 2/20 0.35
LMNA P02545 2/20 0.35
TP53 P04637 2/20 0.35
GPR119 Q8TDV5 1/20 0.35
POLB P06746 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TSHR P16473 1/20 0.34
P2RX7 Q99572 1/20 0.34
KDM1A O60341 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPK8 P45983 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31076463 0.85 GPR119 (0.43) EPHA2ERBB2EPHB4MAPTSTS
SCHEMBL31076423 0.85 EPHA2 (0.41) EPHA2ERBB2EPHB4MAPTSTS
SCHEMBL31076369 0.83 EPHA2 (0.42) EPHA2ERBB2EPHB4MAPTSTS
SCHEMBL31076468 0.83 USP30 (0.42) EPHA2ERBB2EPHB4MAPTRET
SCHEMBL31076418 0.82 EPHA2 (0.42) EPHA2ERBB2EPHB4MAPTSTS
SCHEMBL31076489 0.81 EPHA2 (0.41) EPHA2ERBB2EPHB4MAPTSTS
SCHEMBL31076372 0.81 MAPT (0.43) EPHA2ERBB2EPHB4MAPTSTS
SCHEMBL31076379 0.80 GPR119 (0.42) EPHA2ERBB2EPHB4MAPTSTS
SCHEMBL31076410 0.80 EPHA2 (0.41) EPHA2ERBB2EPHB4MAPTSTS
SCHEMBL31076429 0.79 MAPT (0.46) EPHA2ERBB2EPHB4MAPTSTS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642778-A1 LSD1 MODULATORS Recursion Pharmaceuticals, Inc. (US) 2025-11-05 EP disclosed
WO-2024141757-A1 LSD1 MODULATORS EXSCIENTIA AI LIMITED (GB) 2024-07-04 WO disclosed