SCHEMBL31076457

SCHEMBL31076457

CC(C)(C)OC(=O)N[C@H]1C[C@H]2CC[C@@H]1N2Cc1cccc(Cl)c1C1CCC1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
REN P00797 1/20 0.39
CXCR6 O00574 1/20 0.39
DRD2 P14416 4/20 0.38
DRD3 P35462 1/20 0.38
CCR1 P32246 1/20 0.35
BTK Q06187 1/20 0.34
SLC16A3 O15427 2/20 0.34
SLC16A1 P53985 2/20 0.34
MCTS1 Q9ULC4 2/20 0.34
SLC6A3 Q01959 1/20 0.34
KDM1A O60341 1/20 0.34
MAOB P27338 1/20 0.34
CYP3A4 P08684 3/20 0.33
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31076435 0.86 KMT2A (0.47) KMT2AL3MBTL1RENCXCR6DRD2
SCHEMBL31076330 0.84 KMT2A (0.46) KMT2AL3MBTL1RENCXCR6DRD2
SCHEMBL31076440 0.84 KMT2A (0.45) KMT2AL3MBTL1RENCXCR6DRD2
SCHEMBL31076350 0.81 KMT2A (0.43) KMT2AL3MBTL1RENCXCR6DRD2
SCHEMBL31076540 0.81 KMT2A (0.43) KMT2AL3MBTL1RENCXCR6DRD2
SCHEMBL31076438 0.79 KMT2A (0.41) KMT2AL3MBTL1RENCXCR6DRD2
SCHEMBL31076377 0.76 L3MBTL1 (0.42) KMT2AL3MBTL1RENCXCR6DRD2
SCHEMBL31076436 0.75 KDM1A (0.43) KDM1A
SCHEMBL31076346 0.75 KMT2A (0.49) KMT2AL3MBTL1DRD2DRD3SLC6A3
SCHEMBL24976021 0.75 L3MBTL1 (0.53) KMT2AL3MBTL1KDM1ACYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642778-A1 LSD1 MODULATORS Recursion Pharmaceuticals, Inc. (US) 2025-11-05 EP disclosed
WO-2024141757-A1 LSD1 MODULATORS EXSCIENTIA AI LIMITED (GB) 2024-07-04 WO disclosed