Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25747909 | 1.00 | MAPK14 (0.39) | MAPK14KDM4EMAPK1ALDH1A1MAPT | |
| SCHEMBL25424702 | 0.91 | ALDH1A1 (0.40) | MAPK14KDM4EMAPK1ALDH1A1MAPT | |
| SCHEMBL31077720 | 0.89 | KDM4E (0.39) | MAPK14KDM4EMAPK1ALDH1A1MEN1 | |
| SCHEMBL25747942 | 0.89 | KDM4E (0.39) | MAPK14KDM4EMAPK1ALDH1A1MEN1 | |
| SCHEMBL25747933 | 0.87 | ALDH1A1 (0.38) | MAPK14KDM4EMAPK1ALDH1A1MAPT | |
| SCHEMBL25747875 | 0.85 | MAPK14 (0.47) | MAPK14KDM4EMAPK1MAPTGABRP | |
| SCHEMBL31077755 | 0.85 | MAPK14 (0.47) | MAPK14KDM4EMAPK1MAPTGABRP | |
| SCHEMBL25747925 | 0.84 | ALDH1A1 (0.41) | MAPK14KDM4EMAPK1ALDH1A1MAPT | |
| SCHEMBL25747919 | 0.81 | MAPK14 (0.38) | MAPK14KDM4EMAPK1GABRPGABRD | |
| SCHEMBL25438668 | 0.81 | ALDH1A1 (0.38) | MAPK14KDM4EMAPK1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118715204-A | Compounds of formula (I) | 普赛洛私人有限公司 | 2024-09-27 | — | — | CN | disclosed |