Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 9/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 8/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 8/20 | 0.42 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5074903 | 0.84 | PIK3CD (0.47) | PIK3CDCSNK2A2CSNK2A1 | |
| SCHEMBL31078253 | 0.83 | PIK3CD (0.54) | PIK3CDCSNK2A2CSNK2A1 | |
| SCHEMBL5077184 | 0.78 | PIK3CD (0.62) | PIK3CDCSNK2A2CSNK2A1 | |
| SCHEMBL14327056 | 0.75 | CSNK2A2 (0.43) | PIK3CDCSNK2A2CSNK2A1 | |
| SCHEMBL5077780 | 0.74 | PIK3CD (0.55) | PIK3CDCSNK2A2CSNK2A1ACVRL1 | |
| SCHEMBL14327060 | 0.74 | PIK3CD (0.58) | PIK3CD | |
| SCHEMBL5141113 | 0.74 | PIK3CD (0.55) | PIK3CDCSNK2A2CSNK2A1ACVRL1 | |
| SCHEMBL19690039 | 0.73 | PIK3CD (0.61) | PIK3CDCSNK2A2CSNK2A1 | |
| SCHEMBL14888138 | 0.73 | PIK3CD (0.58) | PIK3CDACVRL1 | |
| SCHEMBL64680 | 0.73 | ALDH1A1 (0.42) | PIK3CDACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665733-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | Bristol-Myers Squibb Company (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173323-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-22 | — | — | WO | disclosed |