Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | XDH | P47989 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1529854 | 0.83 | DAO (0.43) | DAOHPGDKDM4EMAPK1ALDH1A1 | |
| SCHEMBL16302070 | 0.81 | DAO (0.69) | DAOHPGDKDM4EMAPK1ALDH1A1 | |
| SCHEMBL1529851 | 0.79 | DAO (0.43) | DAOHPGDKDM4EMAPK1ALDH1A1 | |
| SCHEMBL5467194 | 0.79 | ABL1 (0.46) | DAOHPGDKDM4EMAPK1ALDH1A1 | |
| SCHEMBL577650 | 0.78 | MAPT (0.45) | HPGDKDM4EMAPK1ALDH1A1NPC1 | |
| SCHEMBL10286930 | 0.77 | DAO (0.41) | DAOHPGDKDM4EMAPK1ALDH1A1 | |
| SCHEMBL1561317 | 0.76 | OPRD1 (0.43) | HPGDKDM4EMAPK1ALDH1A1NPC1 | |
| SCHEMBL424946 | 0.74 | USP10 (0.47) | MAPK1ALDH1A1LMNAPOLBTDP1 | |
| SCHEMBL19439584 | 0.73 | PTPN2 (0.49) | HPGDKDM4EMAPK1ALDH1A1NPC1 | |
| SCHEMBL20892550 | 0.72 | MRGPRX4 (0.43) | DAOHPGDKDM4EMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665733-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | Bristol-Myers Squibb Company (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173323-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-22 | — | — | WO | disclosed |