Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205839 | 0.80 | PTPN1 (0.57) | CNR2CNR1KDM4ELMNACASP1 | |
| SCHEMBL14045624 | 0.78 | CNR2 (0.46) | CNR2CNR1KDM4EPTPN1GPR3 | |
| SCHEMBL2388976 | 0.78 | CNR2 (0.46) | CNR2CNR1KDM4EPTPN1GPR3 | |
| SCHEMBL11381301 | 0.77 | MEN1 (0.46) | CNR2KDM4ELMNACASP1PTPN1 | |
| SCHEMBL11959206 | 0.76 | LOXL2 (0.69) | CNR2CNR1KDM4EGPR3LOXL2 | |
| SCHEMBL22810223 | 0.76 | CNR2 (0.45) | CNR2CNR1KDM4EPTPN1GPR3 | |
| SCHEMBL13352406 | 0.76 | CNR2 (0.45) | CNR2CNR1KDM4ELMNACASP1 | |
| SCHEMBL11189813 | 0.76 | MAPT (0.47) | KDM4ELMNALOXL2MAPTRAB9A | |
| SCHEMBL10274323 | 0.73 | CNR2 (0.43) | CNR2CNR1KDM4EPTPN1GPR3 | |
| SCHEMBL11321079 | 0.73 | NPY1R (0.49) | CNR2CNR1LMNAPTPN1GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665733-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | Bristol-Myers Squibb Company (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173323-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-22 | — | — | WO | disclosed |