⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4992997 | 1.00 | — | — | |
| SCHEMBL27440287 | 1.00 | — | — | |
| Thiophene SCHEMBL28192766 | 0.86 | — | — | |
| SCHEMBL27865051 | 0.83 | — | — | |
| SCHEMBL27611847 | 0.72 | SLC6A2 (0.30) | — | |
| SCHEMBL4763930 | 0.69 | — | — | |
| SCHEMBL11086680 | 0.69 | — | — | |
| SCHEMBL3159845 | 0.69 | — | — | |
| SCHEMBL3159809 | 0.68 | ARG1 (0.31) | — | |
| SCHEMBL3591067 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759494-B2 | Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl)ethoxy-carbonyl]-5-oxazolidine carboxylic acids | DABUR INDIA LIMITED (IN) | 2010-07-20 | — | — | US | claimed |
| US-20080064887-A1 | Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl)ethoxycarbon1]-5-oxazolidine carboxylic acids | DABUR INDIA LIMITED (IN) | 2008-03-13 | — | — | US | claimed |
| EP-1797059-A1 | SEMISYNTHESIS PROCESS FOR THE PREPARATION OF 10-DEACETYL-N-DEBENZOYL-PACLITAXEL | INDENA S.p.A. (IT) | 2007-06-20 | — | — | EP | claimed |
| EP-1370541-B1 | METHOD OF PREPARATION OF PACLITAXEL (TAXOL) USING 3-(ALK-2-YNYLOXY) CARBONYL-5-OXAZOLIDINE CARBOXYLIC ACID | DABUR INDIA LTD (IN) | 2006-11-02 | — | — | EP | claimed |
| WO-2006037653-A1 | SEMISYNTHESIS PROCESS FOR THE PREPARATION OF 10-DEACETYL-N-DEBENZOYL-PACLITAXEL | INDENA S.P.A. (IT) | 2006-04-13 | — | — | WO | claimed |
| CN-1205196-C | Process for selective derivatization of taxanes | UNIV FLORIDA STATE (US) | 2005-06-08 | — | — | CN | claimed |
| EP-1370541-A1 | METHOD OF PREPARATION OF PACLITAXEL (TAXOL) USING 3-(ALK-2-YNYLOXY) CARBONYL-5-OXAZOLIDINE CARBOXYLIC ACID | Dabur India Limited (IN) | 2003-12-17 | — | — | EP | claimed |
| US-20030229135-A1 | Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl)ethoxycarbonyl]-5-oxazolidine carboxylic acids | DABUR PHARMA LIMITED (IN) | 2003-12-11 | — | — | US | claimed |
| US-20030013888-A1 | METHOD OF PREPARATION OF PACLITAXEL (TAXOL) USING 3-(ALK-2-YNYLOXY) CARBONYL-5-OXAZOLIDINE CARBOXYLIC ACID | DABUR PHARMA LIMITED (IN) | 2003-01-16 | — | — | US | claimed |
| US-6506905-B1 | Taxol intermediates | DABUR INDIA LIMITED (IN) | 2003-01-14 | — | — | US | claimed |
| WO-2002066448-A1 | METHOD OF PREPARATION OF PACLITAXEL (TAXOL) USING 3-(ALK-2-YNYLOXY) CARBONYL-5-OXAZOLIDINE CARBOXYLIC ACID | DABUR INDIA LIMITED (IN) | 2002-08-29 | — | — | WO | claimed |
| CN-1239476-A | Process for selective derivatization of taxanes | UNIV FLORIDA STATE (US) | 1999-12-22 | — | — | CN | claimed |
| CN-1125575-A | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 1996-07-03 | — | — | CN | claimed |
| US-12246081-B2 | Deodorant compositions | CONOPCO, INC. (US) | 2025-03-11 | — | — | US | disclosed |
| EP-3727314-B1 | DEODORANT COMPOSITIONS | UNILEVER IP HOLDINGS B V (NL) | 2021-10-13 | — | — | EP | disclosed |
| CN-113318001-A | Skin cleanser and lamellar formation promoter containing Trehangelin | 株式会社芳珂 | 2021-08-31 | — | — | CN | disclosed |
| US-5545838-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-08-13 | — | — | US | disclosed |
| CN-1125575-A | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 1996-07-03 | — | — | CN | disclosed |
| US-5098924-A | Hypotensive agents and angiotensin II inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0452587-A1 | Dihydroxy sulfonamide and sulfinamide renin inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1991-10-23 | — | — | EP | disclosed |