Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.47 |
| ▸ | RELA | Q04206 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25706410 | 1.00 | KMT2A (0.55) | KMT2AMEN1PKMGFERNPC1 | |
| SCHEMBL3595919 | 1.00 | KMT2A (0.55) | KMT2AMEN1PKMGFERNPC1 | |
| SCHEMBL3595923 | 1.00 | KMT2A (0.55) | KMT2AMEN1PKMGFERNPC1 | |
| SCHEMBL31515000 | 0.87 | ALDH1A1 (0.62) | KMT2AMEN1PKMGFERNPC1 | |
| SCHEMBL30392364 | 0.87 | ALDH1A1 (0.62) | KMT2AMEN1PKMGFERNPC1 | |
| SCHEMBL25236997 | 0.87 | ALDH1A1 (0.62) | KMT2AMEN1PKMGFERNPC1 | |
| SCHEMBL25272508 | 0.87 | ALDH1A1 (0.62) | KMT2AMEN1PKMGFERNPC1 | |
| SCHEMBL15755020 | 0.86 | SRC (0.50) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15755021 | 0.86 | SRC (0.50) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31079434 | 0.85 | KDM4E (0.53) | KMT2AMEN1PKMGFERNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118647606-A | Benzothiophene derivatives as RXFP1 agonists | 百时美施贵宝公司 | 2024-09-13 | — | — | CN | disclosed |