Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31079543 | 0.79 | EP300 (0.49) | EP300GPR84FFAR1FFAR4MAPT | |
| SCHEMBL31079605 | 0.74 | EP300 (0.47) | EP300GPR84FFAR1FFAR4MAPT | |
| SCHEMBL9420270 | 0.74 | EP300 (0.50) | EP300 | |
| Methacrylic Acid SCHEMBL28070838 | 0.72 | EP300 (0.40) | EP300GPR84FFAR1FFAR4FNTA | |
| SCHEMBL8518465 | 0.70 | EP300 (0.40) | EP300GPR84FFAR1FFAR4FNTA | |
| SCHEMBL3679830 | 0.69 | EP300 (0.45) | EP300GPR84FFAR1FFAR4FNTA | |
| SCHEMBL21065579 | 0.69 | EP300 (0.45) | EP300GPR84FFAR1FFAR4FNTA | |
| SCHEMBL157091 | 0.69 | EP300 (0.45) | EP300GPR84FFAR1FFAR4FNTA | |
| SCHEMBL21065587 | 0.69 | EP300 (0.45) | EP300GPR84FFAR1FFAR4FNTA | |
| SCHEMBL22607803 | 0.69 | EP300 (0.45) | EP300GPR84FFAR1FFAR4FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240341301-A1 | ITACONATE AND DERIVATIVES THEREOF FOR THE PROTECTION OF CELLS, TISSUES, AND ORGANS | UNIV MICHIGAN REGENTS (US) | 2024-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240341301-A1 | ITACONATE AND DERIVATIVES THEREOF FOR THE PROTECTION OF CELLS, TISSUES, AND ORGANS | TNNI3, ALDH2, ALDH5A1 | EP300 3264/4885GPR84 4585/4885FFAR1 2394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.