Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | GLA | P06280 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | CFTR | P13569 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2961556 | 1.00 | ALDH1A1 (0.59) | ALDH1A1KDM4EGLAHPGDHSD17B10 | |
| SCHEMBL15697523 | 0.89 | ALDH1A1 (0.59) | ALDH1A1KDM4EGLAHPGDHSD17B10 | |
| SCHEMBL8136940 | 0.86 | KDM4E (0.51) | ALDH1A1KDM4EGLAHPGDHSD17B10 | |
| SCHEMBL693338 | 0.85 | MAPT (0.51) | ALDH1A1KDM4EGLAHPGDHSD17B10 | |
| SCHEMBL717432 | 0.85 | ALDH1A1 (0.48) | ALDH1A1KDM4EGLAHPGDHSD17B10 | |
| SCHEMBL6844839 | 0.85 | ALDH1A1 (0.48) | ALDH1A1KDM4EGLAHPGDHSD17B10 | |
| SCHEMBL693546 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KDM4EGLAHPGDHSD17B10 | |
| SCHEMBL25284722 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL31079515 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL2955131 | 0.82 | ALDH1A1 (0.64) | ALDH1A1KDM4EGLAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118647606-A | Benzothiophene derivatives as RXFP1 agonists | 百时美施贵宝公司 | 2024-09-13 | — | — | CN | disclosed |