Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 10/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18990470 | 0.92 | CA12 (0.43) | SUCNR1CA12CA1CA2CA9 | |
| SCHEMBL18990469 | 0.92 | CA12 (0.43) | SUCNR1CA12CA1CA2CA9 | |
| SCHEMBL20566580 | 0.80 | SUCNR1 (0.42) | SUCNR1CA12CA1CA2CA9 | |
| SCHEMBL20566583 | 0.80 | SUCNR1 (0.42) | SUCNR1CA12CA1CA2CA9 | |
| SCHEMBL23827436 | 0.79 | SUCNR1 (0.43) | SUCNR1CA1CA2NPSR1 | |
| SCHEMBL23827435 | 0.79 | SUCNR1 (0.43) | SUCNR1CA1CA2NPSR1 | |
| SCHEMBL29101097 | 0.79 | SUCNR1 (0.43) | SUCNR1CA1CA2NPSR1 | |
| SCHEMBL20566735 | 0.76 | SUCNR1 (0.46) | SUCNR1CA12CA1CA2CA9 | |
| SCHEMBL18990569 | 0.76 | SUCNR1 (0.47) | SUCNR1CA12CA1CA2CA9 | |
| SCHEMBL20566736 | 0.76 | SUCNR1 (0.46) | SUCNR1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368040-B | Diaryl monocyclic beta-lactam compounds and methods for their use in the treatment of bacterial infections | 默沙东有限责任公司 | 2024-08-23 | — | — | CN | disclosed |