Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 8/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23827435 | 1.00 | SUCNR1 (0.43) | SUCNR1HDAC4HDAC1SIRT5HDAC3 | |
| SCHEMBL23827436 | 1.00 | SUCNR1 (0.43) | SUCNR1HDAC4HDAC1SIRT5HDAC3 | |
| SCHEMBL29101054 | 0.93 | TDP1 (0.43) | SUCNR1HDAC4HDAC1SIRT5HDAC3 | |
| SCHEMBL29101055 | 0.93 | TDP1 (0.43) | SUCNR1HDAC4HDAC1SIRT5HDAC3 | |
| SCHEMBL23838013 | 0.90 | CA1 (0.39) | SUCNR1HDAC4HDAC1SIRT5HDAC3 | |
| SCHEMBL23827392 | 0.84 | PSMB8 (0.41) | SUCNR1HDAC4HDAC1SIRT5HDAC3 | |
| SCHEMBL23827389 | 0.84 | PSMB8 (0.41) | SUCNR1HDAC4HDAC1SIRT5HDAC3 | |
| SCHEMBL22012933 | 0.80 | CA1 (0.48) | HDAC4HDAC1SIRT5HDAC3HDAC7 | |
| SCHEMBL22012931 | 0.80 | CA1 (0.48) | HDAC4HDAC1SIRT5HDAC3HDAC7 | |
| SCHEMBL31080074 | 0.79 | SUCNR1 (0.43) | SUCNR1CA1CA2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111171014-B | Monocyclolactam compounds and uses thereof | 南京圣和药业股份有限公司 | 2023-11-07 | — | — | CN | disclosed |