Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.35 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25885735 | 1.00 | ALDH1A1 (0.36) | ALDH1A1KCNH2PIK3C2APIK3C2BPIK3CA | |
| SCHEMBL31081648 | 0.94 | ALDH1A1 (0.37) | ALDH1A1KCNH2PIK3C2APIK3C2BPIK3CA | |
| SCHEMBL25886049 | 0.94 | ALDH1A1 (0.37) | ALDH1A1KCNH2PIK3C2APIK3C2BPIK3CA | |
| SCHEMBL25886092 | 0.92 | ALDH1A1 (0.32) | ALDH1A1KCNH2 | |
| SCHEMBL25886035 | 0.90 | PIK3C2A (0.35) | ALDH1A1KCNH2PIK3C2APIK3C2BPIK3CA | |
| SCHEMBL30989762 | 0.90 | PIK3C2A (0.35) | ALDH1A1KCNH2PIK3C2APIK3C2BPIK3CA | |
| SCHEMBL31081847 | 0.89 | POLB (0.32) | POLB | |
| SCHEMBL25886061 | 0.89 | POLB (0.32) | POLB | |
| SCHEMBL25885940 | 0.89 | POLB (0.32) | POLB | |
| SCHEMBL25885544 | 0.89 | ALDH1A1 (0.35) | ALDH1A1KCNH2PIK3C2APIK3C2BPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175558-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYL-SULFONE/SULFOXIMINE-PYRIDINE N-OXIDE DERIVATIVES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-08-29 | — | — | WO | disclosed |