Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | HCK | P08631 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31083319 | 0.85 | LRRK2 (0.44) | LRRK2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL31083327 | 0.82 | LRRK2 (0.37) | LRRK2RXFP1 | |
| SCHEMBL22324524 | 0.79 | EGFR (0.34) | MAPTPIK3CDABL1EGFRHCK | |
| SCHEMBL25213735 | 0.79 | LRRK2 (0.47) | LRRK2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL29380274 | 0.79 | LRRK2 (0.47) | LRRK2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL28644933 | 0.77 | TNF (0.37) | LMNAMAPTPIK3CDABL1EGFR | |
| SCHEMBL30186361 | 0.77 | TNF (0.37) | LMNAMAPTPIK3CDABL1EGFR | |
| SCHEMBL29702360 | 0.75 | LRRK2 (0.50) | LRRK2ALDH1A1GAAMAPTHTT | |
| SCHEMBL26100427 | 0.75 | LRRK2 (0.50) | LRRK2ALDH1A1GAAMAPTHTT | |
| SCHEMBL31083005 | 0.73 | ERCC1 (0.35) | LRRK2ALDH1A1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182747-A2 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |