Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839089 | 0.83 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL16080089 | 0.81 | RAB9A (0.58) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL3727157 | 0.81 | MEN1 (0.72) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL9839006 | 0.74 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL28758405 | 0.74 | MAPT (0.49) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL12787954 | 0.74 | RAB9A (0.52) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL14966349 | 0.72 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3466719 | 0.70 | SMN1; SMN2 (0.59) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2097746 | 0.69 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL11705133 | 0.67 | PTGDR2 (0.51) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182380-A2 | SUBSTITUTED THIADIAZOLYL COMPOUNDS | CYTEIR THERAPEUTICS, INC. (US) | 2024-09-06 | — | — | WO | disclosed |