SCHEMBL3108329

SCHEMBL3108329

O=C(O)C=CC(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5319389 1.00
SCHEMBL5532569 0.81 GABRP (0.48)
SCHEMBL28319563 0.77 GABRP (0.44)
SCHEMBL28638529 0.77 GABRP (0.44)
SCHEMBL3320981 0.77
SCHEMBL6064000 0.77
SCHEMBL15545952 0.77 GABRP (0.44)
Bicarbonate SCHEMBL20423774 0.76 CA1 (0.39)
SCHEMBL12139574 0.73 TSHR (0.53)
SCHEMBL21610070 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112794782-A Fluorine-containing carboxylic acid compound and preparation method thereof 四川大学 2021-05-14 CN claimed
US-12612414-B2 Nitrile SUMO inhibitors and uses thereof CIT THERAPEUTICS, INC. (US) 2026-04-28 US disclosed
US-12606572-B2 Substituted heterocycles and uses thereof KUMQUAT BIOSCIENCES INC. (US) 2026-04-21 US disclosed
EP-4724445-A1 SUBSTITUTED HETEROCYCLES AND USES THEREOF Kumquat Biosciences Inc. (US) 2026-04-15 EP disclosed
US-20260028357-A1 SUBSTITUTED HETEROCYCLES AND USES THEREOF KUMQUAT BIOSCIENCES INC (US) 2026-01-29 US disclosed
US-12398151-B2 Sumo inhibitor compounds and uses thereof Suvalent Therapeutics, Inc. (US) 2025-08-26 US disclosed
EP-4419525-B1 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER ARTIOS PHARMA LTD (GB) 2025-07-23 EP disclosed
EP-4519265-A1 IRREVERSIBLE MUTEGFR INHIBITORS Bayer Aktiengesellschaft (DE) 2025-03-12 EP disclosed
US-20250074881-A1 THERAPEUTIC COMPOUNDS AND METHODS OF USE GENENTECH, INC. (US) 2025-03-06 US disclosed
US-20250059163-A1 FUSED RING COMPOUNDS GENENTECH INC (US) 2025-02-20 US disclosed
US-20150291554-A1 Bruton's Tyrosine Kinase Inhibitors PFIZER (US) 2015-10-15 US disclosed
US-20150259346-A1 HEXAHYDRODIAZEPINOQUINOLINES CARRYING A SUBSTITUTED ALKYL RADICAL AbbVie Deutschland GmbH & Co. KG (DE) 2015-09-17 US disclosed
WO-2015136091-A1 HEXAHYDRODIAZEPINOQUINOLINES CARRYING A SUBSTITUTED ALKYL RADICAL AbbVie Deutschland GmbH & Co. KG (DE) 2015-09-17 WO disclosed
EP-2914586-A1 BRUTON'S TYROSINE KINASE INHIBITORS Pfizer Inc. (US) 2015-09-09 EP disclosed
WO-2014068527-A1 BRUTON'S TYROSINE KINASE INHIBITORS PFIZER INC. (US) 2014-05-08 WO disclosed
US-8507189-B2 Upper layer film forming composition and method of forming photoresist pattern JSR CORPORATION (JP) 2013-08-13 US disclosed
US-8431332-B2 Composition for forming upper layer film for immersion exposure, upper layer film for immersion exposure, and method of forming photoresist pattern JSR CORPORATION (JP) 2013-04-30 US disclosed
US-20100255416-A1 COMPOSITION FOR FORMING UPPER LAYER FILM FOR IMMERSION EXPOSURE, UPPER LAYER FILM FOR IMMERSION EXPOSURE, AND METHOD OF FORMING PHOTORESIST PATTERN JSR CORPORATION (JP) 2010-10-07 US disclosed
US-20100040974-A1 UPPER LAYER FILM FORMING COMPOSITION AND METHOD OF FORMING PHOTORESIST PATTERN JSR CORPORATION (JP) 2010-02-18 US disclosed
WO-2007089455-A1 FLUOROALKENYL DERIVATIVES AS INSECTICIDES AND NEMATICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-08-09 WO disclosed