Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 4/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | AXL | P30530 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | CFB | P00751 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3993065 | 1.00 | PRKCI (0.42) | PRKCIAHRPARP1MAPK1DRD4 | |
| SCHEMBL31275318 | 0.83 | PRKCI (0.42) | PRKCIAHRPARP1MAPK1AXL | |
| SCHEMBL2211568 | 0.83 | PRKCI (0.42) | PRKCIAHRPARP1MAPK1AXL | |
| SCHEMBL14041004 | 0.80 | PRKCI (0.36) | PRKCIAHRMAPK1AXL | |
| SCHEMBL31000812 | 0.80 | PRKCI (0.40) | PRKCIAHRMAPK1AXLCCR8 | |
| SCHEMBL25285039 | 0.80 | NUDT1 (0.37) | PRKCIAHRMAPK1AXL | |
| SCHEMBL31000802 | 0.80 | NUDT1 (0.37) | PRKCIAHRMAPK1AXL | |
| SCHEMBL20577529 | 0.80 | PRKCI (0.40) | PRKCIAHRMAPK1AXLCCR8 | |
| SCHEMBL23912514 | 0.80 | PRKCI (0.40) | PRKCIAHRPARP1MAPK1DRD4 | |
| SCHEMBL1763131 | 0.76 | PRKCI (0.41) | PRKCIAHRAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118619943-A | Heteroaromatic ring compound, pharmaceutical composition and application thereof | 上海艾力斯医药科技股份有限公司 | 2024-09-10 | — | — | CN | disclosed |