Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | NPC1 | O15118 | 7/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 7/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 7/20 | 0.57 |
| ▸ | TAS1R2 | Q8TE23 | 7/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25406678 | 1.00 | RAB9A (0.58) | RAB9ANPC1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL30593284 | 0.92 | RAB9A (0.63) | RAB9ANPC1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL25405249 | 0.92 | RAB9A (0.63) | RAB9ANPC1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL31083743 | 0.90 | RAB9A (0.47) | RAB9ANPC1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL25404736 | 0.90 | RAB9A (0.47) | RAB9ANPC1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL25404536 | 0.85 | RAB9A (0.60) | RAB9ANPC1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL30593283 | 0.85 | RAB9A (0.60) | RAB9ANPC1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL30564223 | 0.85 | RAB9A (0.41) | RAB9ANPC1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL25405686 | 0.84 | RAB9A (0.59) | RAB9ANPC1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL30593247 | 0.84 | RAB9A (0.59) | RAB9ANPC1TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118742543-A | Dihydro isoquinoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-10-01 | — | — | CN | disclosed |