SCHEMBL31083812

SCHEMBL31083812

Cc1cc(-c2ccc(CC(=O)Nc3ncc(-c4cnccn4)cc3C)cn2)ccn1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ WNT3A P56704 19/20 0.76
▸ PORCN Q9H237 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1722771 0.86 WNT3A (1.00) WNT3APORCN
SCHEMBL1723597 0.77 WNT3A (1.00) WNT3APORCN
SCHEMBL1723533 0.76 WNT3A (1.00) WNT3APORCN
SCHEMBL1722861 0.75 WNT3A (1.00) WNT3A
Wnt-974 SCHEMBL1723611 0.75 WNT3A (1.00) WNT3APORCN
Wnt-974 SCHEMBL29351311 0.75 WNT3A (1.00) WNT3APORCN
Wnt-974 SCHEMBL29382356 0.75 WNT3A (1.00) WNT3APORCN
SCHEMBL1723571 0.75 WNT3A (1.00) WNT3A
SCHEMBL1726039 0.74 WNT3A (1.00) WNT3APORCN
SCHEMBL1724840 0.74 WNT3A (1.00) WNT3APORCN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2024133495-A DOSING SCHEDULE OF WNT INHIBITOR AND ANTI-PD-1 ANTIBODY MOLECULE IN COMBINATION ノバルティス アーゲー 2024-10-02 — — JP disclosed
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