Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.31 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | CKS1B | P61024 | 1/20 | 0.31 |
| ▸ | SKP1 | P63208 | 1/20 | 0.31 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31083999 | 0.93 | PIK3R1 (0.34) | PIK3R1PIK3CAGPR119CKS1BSKP1 | |
| SCHEMBL31002984 | 0.86 | CACNA1B (0.34) | PIK3R1PIK3CA | |
| SCHEMBL31002983 | 0.85 | PIK3R1 (0.32) | PIK3R1PIK3CA | |
| Nerandomilast SCHEMBL14734178 | 0.84 | PIK3R1 (0.34) | PIK3R1PIK3CA | |
| Nerandomilast SCHEMBL25606332 | 0.84 | PIK3R1 (0.34) | PIK3R1PIK3CA | |
| SCHEMBL31084026 | 0.83 | — | — | |
| SCHEMBL31084045 | 0.81 | PIK3R1 (0.30) | PIK3R1PIK3CA | |
| SCHEMBL30678851 | 0.81 | PIK3R1 (0.33) | PIK3R1PIK3CA | |
| SCHEMBL31438850 | 0.81 | PIK3R1 (0.33) | PIK3R1PIK3CA | |
| SCHEMBL31083968 | 0.80 | PIK3R1 (0.32) | PIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4674852-A1 | PREPARATION METHOD FOR AND USE OF DIHYDROTHIENOPYRIMIDINE DERIVATIVE | Innovstone Therapeutics Limited (CN) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024179493-A1 | PREPARATION METHOD FOR AND USE OF DIHYDROTHIENOPYRIMIDINE DERIVATIVE | 上海翊石医药科技有限公司 | 2024-09-06 | — | — | WO | disclosed |