SCHEMBL31084020

SCHEMBL31084020

CC(C)(O)c1ccc(-c2nc3c(c(NC4(CO)CCC4)n2)[S@+]([O-])CC3)cc1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ LATS1 O95835 6/20 0.40
▸ LATS2 Q9NRM7 3/20 0.40
▸ TRPV3 Q8NET8 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31084006 0.91 LATS1 (0.40) LATS1LATS2TRPV3
SCHEMBL31083981 0.89 TRPV3 (0.44) LATS1LATS2TRPV3
SCHEMBL31084007 0.89 LATS1 (0.38) LATS1LATS2TRPV3
SCHEMBL31083976 0.89 LATS1 (0.38) LATS1LATS2TRPV3
SCHEMBL31083967 0.87 LATS1 (0.37) LATS1LATS2TRPV3
SCHEMBL31083959 0.86 LATS1 (0.43) LATS1LATS2TRPV3
SCHEMBL31083963 0.85 LATS1 (0.41) LATS1LATS2
SCHEMBL31083971 0.84 LATS1 (0.35) LATS1LATS2
SCHEMBL31083989 0.83 LATS1 (0.41) LATS1LATS2
SCHEMBL31084001 0.83 LATS1 (0.39) LATS1LATS2TRPV3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4674852-A1 PREPARATION METHOD FOR AND USE OF DIHYDROTHIENOPYRIMIDINE DERIVATIVE Innovstone Therapeutics Limited (CN) 2026-01-07 — — EP disclosed
CN-118871444-A Preparation method and application of dihydro-thienopyrimidine derivative 上海翊石医药科技有限公司 2024-10-29 — — CN disclosed
WO-2024179493-A1 PREPARATION METHOD FOR AND USE OF DIHYDROTHIENOPYRIMIDINE DERIVATIVE 上海翊石医药科技有限公司 2024-09-06 — — WO disclosed
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