Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.41 |
| ▸ | OPA1 | O60313 | 1/20 | 0.39 |
| ▸ | EIF5B | O60841 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2016725 | 0.86 | S1PR1 (0.46) | HTR2AHTR2CMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL20365440 | 0.77 | HTR2A (0.54) | HTR2AHTR2CMTNR1AMTNR1BOPA1 | |
| SCHEMBL2019229 | 0.74 | KDM4E (0.47) | HTR2AHTR2COPA1EIF5BMET | |
| SCHEMBL10100276 | 0.74 | HTR2A (0.59) | HTR2AHTR2CMTNR1AMTNR1BOPA1 | |
| SCHEMBL23691134 | 0.72 | HTR2A (0.55) | HTR2AHTR2CMTNR1AMTNR1BOPA1 | |
| SCHEMBL13087200 | 0.72 | MTNR1A (0.50) | HTR2AHTR2CMTNR1AMTNR1BOPA1 | |
| SCHEMBL2020405 | 0.72 | NPC1 (0.43) | HTR2AHTR2CMTNR1AMTNR1BUSP2 | |
| SCHEMBL2020595 | 0.71 | HTR2A (0.42) | HTR2AHTR2CMTNR1AMTNR1BOPA1 | |
| SCHEMBL2018600 | 0.70 | HTR2A (0.46) | HTR2AHTR2CMTNR1AMTNR1BOPA1 | |
| SCHEMBL1395855 | 0.70 | HTR2A (0.55) | HTR2AHTR2CMTNR1AMTNR1BUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108960-B | Preparation method and application of polysubstituted indole compound | 陕西蒲城万德科技有限公司 | 2024-08-27 | — | — | CN | disclosed |