Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCK | P08631 | 9/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 9/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28577141 | 1.00 | HCK (0.35) | HCKMAPK12MAPK14SRCNR3C2 | |
| SCHEMBL31086673 | 0.88 | IKBKE (0.40) | HCKMAPK12MAPK14SRCMRGPRX4 | |
| SCHEMBL17008526 | 0.88 | IKBKE (0.40) | HCKMAPK12MAPK14SRCMRGPRX4 | |
| SCHEMBL28579283 | 0.87 | LMNA (0.39) | HCKMAPK12MAPK14SRCMRGPRX4 | |
| SCHEMBL17008508 | 0.86 | HCK (0.36) | HCKMAPK12MAPK14SRCNR3C2 | |
| SCHEMBL17017129 | 0.85 | MRGPRX4 (0.40) | HCKMAPK12MAPK14SRCNR3C2 | |
| Hydrochloric Acid SCHEMBL17008549 | 0.84 | MRGPRX4 (0.40) | HCKMAPK12MAPK14SRCNR3C2 | |
| SCHEMBL17008477 | 0.83 | MRGPRX4 (0.39) | HCKMAPK12MAPK14SRCNR3C2 | |
| SCHEMBL18546352 | 0.83 | HCK (0.37) | HCKMAPK12MAPK14SRCNR3C2 | |
| SCHEMBL18567057 | 0.82 | HDAC1 (0.39) | HCKMAPK12MAPK14SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264921-B | Pyrazolyl-ureas as kinase inhibitors | 瑞斯比维特有限公司 | 2024-09-13 | — | — | CN | disclosed |