Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31087030 | 0.83 | CYP2D6 (0.48) | GSK3BSLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL19617795 | 0.83 | HTR2A (0.38) | SORDGSK3BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21360414 | 0.82 | PLD1 (0.54) | SORDFPR2SCN9ASLC6A2SLC6A4 | |
| SCHEMBL21360320 | 0.82 | PLD1 (0.54) | SORDFPR2SCN9ASLC6A2SLC6A4 | |
| SCHEMBL21360315 | 0.79 | SORD (0.38) | SORDFPR2SCN9AHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL31087008 | 0.78 | SLC6A2 (0.36) | FPR2SCN9ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15106791 | 0.78 | GSK3B (0.40) | SORDGSK3BHTR2AHTR2CHTR2B | |
| SCHEMBL27693766 | 0.78 | SORD (0.43) | SORD | |
| SCHEMBL28127174 | 0.77 | CUL4A (0.46) | SORDNOS2 | |
| SCHEMBL28127175 | 0.77 | CUL4A (0.46) | SORDNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676547-A2 | ALPHA-SYNUCLEIN BINDERS AND METHODS OF USE | Merck Sharp & Dohme LLC (US) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024186584-A2 | ALPHA-SYNUCLEIN BINDERS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2024-09-12 | — | — | WO | disclosed |